The current aim of our research work is to isolate the biomaterial from fruit pulp of Annona squamosa and evaluate its binding ability. The fruit pulp was subjected for isolating the biomaterial in a simplified and economic process. Using this biomaterial, granules were prepared taking diclofenac as a model drug. The granules were evaluated through various parameters like flowability, compressibility index, dispersibility, particle size, particle shape, hausner index, disintegration test, friability, angle of repose, bulk density and breaking strength. The research results revealed that the formulated granules using biomaterial show free flowing property with optimum breaking strength, significant dispersibility, and sufficient compressibility comparable to standard granules prepared using starch. Hence it can serve as novel potential biobinder for formulating tablets.
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